Cr1l ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCr1l ELISA Kit for Rat(Rattus norvegicus)

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Cr1l (Gene name),

Complement component receptor 1-like protein (Protein name ), CR1L_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cr1l(Crry);

Protein name:

Complement component receptor 1-like protein;

Alternative:

Complement regulatory protein Crry;Antigen 5I2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with C3b.

Function:

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Seems to act as a costimulatory factor for T-cells. May play a crucial role in early embryonic development by maintaining fetomaternal tolerance.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

559

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

559:

ARNSLTQEV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q63135

KEGG:

rno:54243

Pfam:

PF00084

UniGene:

Rn.5825

Uniprot:

Q63135

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ELISA Kit for Rat Complement component receptor 1-like protein

Cat.:

E15277h

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MSDS:

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Packing:

96T

ELISA Kit for Rat Complement component receptor 1-like protein

Cat.:

E15277m

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MSDS:

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Packing:

96T

ELISA Kit for Rat Complement component receptor 1-like protein

Cat.:

E15277r

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Packing:

96T

CLIA Kit for Rat Complement component receptor 1-like protein

Cat.:

U15277m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Complement component receptor 1-like protein

Cat.:

U15277h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Complement component receptor 1-like protein

Cat.:

U15277r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Complement component receptor 1-like protein

Cat.:

P15277Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Complement component receptor 1-like protein

Cat.:

P15277Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Complement component receptor 1-like protein

Cat.:

P15277Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Complement component receptor 1-like protein

Protein for Rat Complement component receptor 1-like protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of the rat complement regulatory protein, 5I2 antigen."
Sakurada C. , Seno H. , Dohi N. , Takizawa H. , Nonaka M. , Okada N. , Okada H.
Biochem. Biophys. Res. Commun.198:819-826(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Liver.
2.

"Molecular characterization of rat Crry: widespread distribution of two alternative forms of Crry mRNA."
Quigg R.J. , Lo C.F. , Alexander J.J. , Sneed A.E. III , Moxley G.
Immunogenetics42:362-367(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: Sprague-Dawley.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Prostate.
4.

"Complement inhibitor of rat cell membrane resembling mouse Crry/p65."
Takizawa H. , Okada N. , Okada H.
J. Immunol.152:3032-3038(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 39-53; 66-74; 369-373 AND 520-528 (ISOFORM 1);INTERACTION WITH C3B;FUNCTION
5.

"Crry and CD59 regulate complement in rat glomerular epithelial cells and are inhibited by the nephritogenic antibody of passive Heymann nephritis."
Quigg R.J. , Holers V.M. , Morgan B.P. , Sneed A.E. III
J. Immunol.154:3437-3443(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"The role of rat Crry, a complement regulatory protein, in proliferation of thymocytes."
Antic Stankovic J. , Vucevic D. , Majstorovic I. , Vasilijic S. , Colic M.
Life Sci.75:3053-3062(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy."
Aslam M. , Guthridge J.M. , Hack B.K. , Quigg R.J. , Holers V.M. , Perkins S.J.
J. Mol. Biol.329:525-550(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 34-353
8.

"Structures of the rat complement regulator CrrY."
Roversi P. , Johnson S. , Caesar J.J. , McLean F. , Leath K.J. , Tsiftsoglou S.A. , Morgan B.P. , Harris C.L. , Sim R.B. , Lea S.M.
Acta Crystallogr. F67:739-743(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 1-288;DISULFIDE BONDS

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